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Six-year safety evaluation of upadacitinib in moderate-to-severe atopic dermatit...
Upadacitinib demonstrates a stable long-term safety profile in moderate-to-severe atopic dermatitis over six years, with no new or unexpected safety signals obs...
Emerging role of knee bracing in osteoarthritis management
Patients with knee osteoarthritis experience modest gains in pain relief and reported outcomes when compartment-specific knee bracing is integrated into a stand...
Vigorous physical activity and its impact on osteoarthritis-related hip and knee...
Regular vigorous physical activity is strongly linked to better quality of life in adults aged 50 years and older with osteoarthritis and hip and/or knee pain,...
Quality of life outcomes in women suffering from endometriosis: A cross-sectiona...
Endometriosis substantially affects women’s emotional well-being, sleep quality, fertility concerns, and overall daily functioning, with younger women and...
Exploring the causal link between menarche onset and risk of gallstone disease
Earlier age at menarche increases the risk of gallstone disease, with liver function, lipid metabolism, and body fat acting as key mediators.
Clinical outcomes of RefluxStop for gastroesophageal reflux disease
RefluxStop markedly reduces GERD-HRQL scores while maintaining a 95.5% patient satisfaction rate.
Psychological and lifestyle predictors of menstrual symptoms in young women
Rumination is positively associated with increased menstrual symptom severity in young women, while higher pain resilience and physical activity show a protecti...
PDA closure in preterm neonates: Ibuprofen vs. acetaminophen
Intravenous ibuprofen achieves a greater tendency for ductal closure than acetaminophen in premature neonates, with both therapies showing similar safety profil...
Gut health and bile acid diarrhea: Exploring the benefits of low-fat diet
A strong belief that a low-fat diet improves gastrointestinal symptoms significantly influences dietary fat restriction in individuals with bile acid diarrhea.
Failed back surgery syndrome and heart health: What spine surgeons need to know?
Failed back surgery syndrome may signal broader systemic inflammation and increased cardiovascular disease risk.
Connection between SHBG, chronic inflammation, and rheumatoid arthritis outcomes
Higher serum SHBG levels significantly increase rheumatoid arthritis risk and are associated with greater frailty, inflammation, and reduced survival outcomes.
Understanding chronic insomnia treatment preferences: What matters most to patie...
Patients with chronic insomnia prioritize treatments that improve daytime functioning and minimize withdrawal effects, with most preferring treatment over no tr...
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