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Science

111
Summaries

Six-year safety evaluation of upadacitinib in moderate-to-severe atopic dermatit...

Upadacitinib demonstrates a stable long-term safety profile in moderate-to-severe atopic dermatitis over six years, with no new or unexpected safety signals obs...

106
Summaries

Emerging role of knee bracing in osteoarthritis management

Patients with knee osteoarthritis experience modest gains in pain relief and reported outcomes when compartment-specific knee bracing is integrated into a stand...

117
Summaries

Vigorous physical activity and its impact on osteoarthritis-related hip and knee...

Regular vigorous physical activity is strongly linked to better quality of life in adults aged 50 years and older with osteoarthritis and hip and/or knee pain,...

97
Summaries

Quality of life outcomes in women suffering from endometriosis: A cross-sectiona...

Endometriosis substantially affects women’s emotional well-being, sleep quality, fertility concerns, and overall daily functioning, with younger women and...

76
Summaries

Exploring the causal link between menarche onset and risk of gallstone disease

Earlier age at menarche increases the risk of gallstone disease, with liver function, lipid metabolism, and body fat acting as key mediators.

86
Summaries

Clinical outcomes of RefluxStop for gastroesophageal reflux disease

RefluxStop markedly reduces GERD-HRQL scores while maintaining a 95.5% patient satisfaction rate.

122
Summaries

Psychological and lifestyle predictors of menstrual symptoms in young women

Rumination is positively associated with increased menstrual symptom severity in young women, while higher pain resilience and physical activity show a protecti...

108
Summaries

PDA closure in preterm neonates: Ibuprofen vs. acetaminophen

Intravenous ibuprofen achieves a greater tendency for ductal closure than acetaminophen in premature neonates, with both therapies showing similar safety profil...

135
Summaries

Gut health and bile acid diarrhea: Exploring the benefits of low-fat diet

A strong belief that a low-fat diet improves gastrointestinal symptoms significantly influences dietary fat restriction in individuals with bile acid diarrhea.

132
Summaries

Failed back surgery syndrome and heart health: What spine surgeons need to know?

Failed back surgery syndrome may signal broader systemic inflammation and increased cardiovascular disease risk.

118
Summaries

Connection between SHBG, chronic inflammation, and rheumatoid arthritis outcomes

Higher serum SHBG levels significantly increase rheumatoid arthritis risk and are associated with greater frailty, inflammation, and reduced survival outcomes.

220
Summaries

Understanding chronic insomnia treatment preferences: What matters most to patie...

Patients with chronic insomnia prioritize treatments that improve daytime functioning and minimize withdrawal effects, with most preferring treatment over no tr...

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