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# Trending Topics

  • Nimesulide vs Diclofenac to treat osteoarthritis o...

    A double-blind, randomized, phase III clinical trial was conducted to compare nimesulide's safety and efficacy with diclofenac in patients suffering from os...

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  • Nimesulide vs Ibuprofen to treat acute low back pa...

    A randomized, prospective, double-blind, comparative trial was carried out to explore the efficacy and tolerability of nimesulide (a cyclooxygenase-2 [COX-2] se...

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  • Comparable analgesic efficacy of nimesulide and ke...

    A non-randomized trial aimed to explore the efficacy of 100 mg nimesulide and 10 mg ketorolac to manage pain, swelling, and trismus after third molar surgery.

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  • High-dose Omeprazole for pain management in chroni...

    A randomized, prospective, single-blinded, controlled study was carried out to compare 60 mg twice daily Omeprazole + conventional pain medication versus only c...

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  • Ketorolac vs. Ketoprofen for pain management after...

    A double-blind, randomized, prospective, comparative study aimed to compare the effectiveness of postoperative pain relief provided by Ketorolac and Ketoprofen...

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  • Improvement in efficacy of pancreatin in cystic fi...

    In a double-blind, crossover fashion, this study aimed to explore the effect of adding Omeprazole to treatment with pancreatin on fecal fat excretion in adults...

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  • Efficacy of Ketorolac, Paracetamol, and Tramadol f...

    The objective of a prospective, randomized study was to assess the effectiveness, safety, and post-operative pain relief effect of Ketorolac, Paracetamol, and T...

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  • Minoxidil-Spironolactone vs. Minoxidil-Finasteride...

    A blinded randomized clinical trial aimed to evaluate the impact of topical Minoxidil plus oral Spironolactone, as opposed to the topical Minoxidil plus oral Fi...

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  • Comparison of Ibuprofen, Mefenamic Acid and Parace...

    To evaluate and compare the analgesic efficacy of Paracetamol dosed at 600 mg, Ibuprofen dosed at 600 mg, and Mefenamic acid dosed at 500 mg.

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  • Improvement in anesthetic efficacy with Dexamethas...

    A randomized double-blind clinical trial was conducted to assess the anesthetic success rate of 2 mg (4 mg/ml) Dexamethasone added to 2% Lidocaine (with 1:80,00...

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Science

Summaries
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111
Summaries

Six-year safety evaluation of upadacitinib in moderate-to-severe atopic dermatit...

Upadacitinib demonstrates a stable long-term safety profile in moderate-to-severe atopic dermatitis over six years, with no new or unexpected safety signals obs...

106
Summaries

Emerging role of knee bracing in osteoarthritis management

Patients with knee osteoarthritis experience modest gains in pain relief and reported outcomes when compartment-specific knee bracing is integrated into a stand...

117
Summaries

Vigorous physical activity and its impact on osteoarthritis-related hip and knee...

Regular vigorous physical activity is strongly linked to better quality of life in adults aged 50 years and older with osteoarthritis and hip and/or knee pain,...

97
Summaries

Quality of life outcomes in women suffering from endometriosis: A cross-sectiona...

Endometriosis substantially affects women’s emotional well-being, sleep quality, fertility concerns, and overall daily functioning, with younger women and...

76
Summaries

Exploring the causal link between menarche onset and risk of gallstone disease

Earlier age at menarche increases the risk of gallstone disease, with liver function, lipid metabolism, and body fat acting as key mediators.

86
Summaries

Clinical outcomes of RefluxStop for gastroesophageal reflux disease

RefluxStop markedly reduces GERD-HRQL scores while maintaining a 95.5% patient satisfaction rate.

Clinical Research
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1214
Clinical Research

Effectiveness of PCAB vs. high-dose PPI in refractory GERD

PCAB therapy demonstrates superior symptom control compared with double-dose PPI therapy in refractory GERD. The benefit is most significant in those with patho...

670
Clinical Research

Intravenous low-dose butorphanol for prevention of epidural-related maternal fev...

Intravenous butorphanol administered at the onset of epidural analgesia significantly reduces epidural-related maternal fever in parturients. This effect is o...

1001
Clinical Research

Selenium supplementation for Graves–Basedow disease and orbitopathy: A review

Selenium supplementation boosts thyroid hormone levels (TSH, FT4, FT3), reduces thyroid autoantibodies (TPOAb, TgAb, TRAb), and enhances clinical outcomes&mdash...

1204
Clinical Research

Comparative outcomes of GLP-1 receptor agonists in glycemic and weight control

GLP-1RAs improve blood sugar control in T2DM, with tirzepatide being most effective for weight loss in obesity. In normal-weight patients, semaglutide and lirag...

1156
Clinical Research

Lobeglitazone combination therapy improves glycemic control in type 2 diabetes

Lobeglitazone added to metformin and sitagliptin provides a powerful triple therapy that lowers HbA1c by 1%, improves insulin sensitivity, and enhances lipid pr...

2152
Clinical Research

NAAGA vs. azelastine eye drops in allergic conjunctivitis

NAAGA outperforms azelastine in alleviating both symptoms and clinical markers of tear film dysfunction in allergic conjunctivitis, owing to its dual anti-infla...

Case Studies
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377
Case Studies

Magic Mushrooms and Unexpected Toxicity with Severe AKI and Thrombosis

Acute kidney injury (AKI) secondary to toxin exposure is an uncommon but potentially life-threatening condition, particularly when associated with multisystem i...

400
Case Studies

Rare Coexistence of Christmas Tree Ileal Atresia with Intestinal Malrotation in...

This case report describes a rare coexistence of Type IIIb (“Christmas Tree”/Apple Peel) ileal atresia with intestinal malrotation, presenting as ne...

585
Case Studies

Refractory Generalized Pustular Psoriasis in Pregnancy Successfully Treated with...

Generalized pustular psoriasis (GPP) of pregnancy is a rare, life-threatening inflammatory dermatosis associated with significant maternal and fetal morbidity....

491
Case Studies

Diagnostic Value of Gliclazide Challenge Testing in HNF1A Monogenic Diabetes

Hepatocyte nuclear factor-1-alpha maturity-onset diabetes of the young (HNF1A-MODY) is a monogenic form of diabetes that is frequently misinterpreted as type 1...

743
Case Studies

Gastric Devascularization for Severe Upper Gastrointestinal Bleeding in Neonates

In children, severe upper gastrointestinal bleeding is rare and potentially life-threatening. This case describes a 3-day-old male neonate who presented with he...

824
Case Studies

Late Postpartum Type 2 SCAD Presenting as STEMI in a Lactating Woman

SCAD is a rare etiology of ACS, commonly affecting young women in pregnancy or the immediate postpartum period. SCAD presenting several years after childbirth i...

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