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Severe menstrual pain strongly associated with poo...
A new study reports a high incidence of poor sleep quality among female undergraduates and identifies sleep disturbance as an independent predictor of severe dy...
No added bleeding risk with ketorolac: Evidence fr...
A comprehensive meta-analysis of randomized controlled trials (RCTs) confirms that ketorolac, a potent nonsteroidal anti-inflammatory drug (NSAID), does not ele...
1 min
Acetaminophen matches loxoprofen for acute low bac...
In a randomized open-label non-inferiority trial, acetaminophen was found to be as effective as loxoprofen for reducing acute low back pain (LBP)—a findin...
2 min
Oral ibuprofen matches intramuscular ketorolac for...
A prospective, single-center, randomized study has demonstrated that oral ibuprofen is as effective as intramuscular ketorolac in relieving acute, atraumatic mu...
1 min
Therapeutic role of pregabalin in diabetic neuropa...
Diabetic peripheral neuropathy (DPN), a common complication of diabetes, is marked by persistent neuropathic pain that substantially impairs quality of life.
1 min
Pro-inflammatory diets and sciatica: Impact on chr...
Sciatica, a prevalent form of neuropathic pain, is a major contributor to chronic lower back pain, reduced mobility, and functional disability.
1 min
Upadacitinib 15 mg achieves early and durable pain...
In a significant advance for axial spondyloarthritis (axSpA) management, a post-hoc analysis of the phase 2/3 SELECT-AXIS trials reveals that upadacitinib (UPA)...
1 min
Efficacy of intra-articular hyaluronic acid and ke...
Adhesive capsulitis (frozen shoulder) is a painful condition marked by shoulder stiffness, decreased range of motion (ROM), and functional impairment.
2 min
Local iodine dressing vs. antibiotic therapy after...
This study evaluated postoperative symptoms after third molar (wisdom tooth) extraction, focusing on the effectiveness of iodine-based wound dressings.
2 min
Opioid use disorder: New study identifies key risk...
A large retrospective study highlights major risk factors for treatment readmission and mortality in opioid use disorder (OUD), underscoring the impact of psych...
1 min
Emerging role of knee bracing in osteoarthritis management
Patients with knee osteoarthritis experience modest gains in pain relief and reported outcomes when compartment-specific knee bracing is integrated into a stand...
Vigorous physical activity and its impact on osteoarthritis-related hip and knee...
Regular vigorous physical activity is strongly linked to better quality of life in adults aged 50 years and older with osteoarthritis and hip and/or knee pain,...
Structured exercise eases foot pain and improves mobility in rheumatoid arthriti...
Supervised exercise programs reduce foot pain and improve physical function in adults with rheumatoid arthritis, with aquatic exercise, Tai Chi, and high-intens...
Joint-preserving knee surgery shows strong 12-month benefits in medial osteoarth...
Proximal fibular osteotomy improves pain, knee function, joint space width, and varus alignment at 12 months in patients with medial compartment knee osteoarthr...
Chronic disease in children requires careful use of common painkillers
Paracetamol and ibuprofen provide comparable fever and pain relief in children with chronic diseases, but safety risks vary according to comorbidities and clini...
Psychological and lifestyle predictors of menstrual symptoms in young women
Rumination is positively associated with increased menstrual symptom severity in young women, while higher pain resilience and physical activity show a protecti...
Failed back surgery syndrome and heart health: What spine surgeons need to know?
Failed back surgery syndrome may signal broader systemic inflammation and increased cardiovascular disease risk.
BTX injections achieve high response rates in systemic sclerosis–associated digi...
Botulinum toxin injections achieve high healing and response rates in refractory digital ischemia, ulcers, and gangrene in systemic sclerosis, while maintaining...
Loxoprofen sodium cataplasm outperforms flurbiprofen patch in osteoarthritis tri...
Loxoprofen sodium cataplasm provides greater short-term pain relief and functional improvement than flurbiprofen cataplasm in patients with osteoarthritis.
Trial finds comparable pain relief with diclofenac–paracetamol combinations in a...
Intramuscular diclofenac alone provides comparable short-term pain relief to diclofenac combined with oral or IV paracetamol in acute limb injuries, with no sig...
Efficacy of loxoprofen sodium + sodium hyaluronate for osteoarthritis pain relie...
Combination therapy with loxoprofen sodium and sodium hyaluronate improves knee function, reduces pain, and enhances blood rheology in osteoarthritis patients.
14-year study reveals continued pediatric IV acetaminophen overdosing cases
Pediatric IV acetaminophen dosing errors continue to occur in hospitals, revealing a persistent but preventable source of iatrogenic overdose in children.
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